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br Reconsideraciones bio ticas Cuando se exploran
2018-10-25
Reconsideraciones bioéticas Cuando se exploran los problemas tradicionales de la bioética desde una perspectiva feminista, surgen cuestiones familiares lactacystin la bioética y otras más. La bioética feminista nos exige considerar cómo contribuye cada práctica a las relaciones de poder existente
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The above stated models of analysis in which return on
2018-10-25
The above stated models of analysis, in which return on assets and institutional ownership are treated as dependent variables, were estimated using panel data regression. For panel data estimates, the F-test (Baltagi, 1995) and the Breusch and Pagan (1980) Lagrange Multiplier test (B–P) were perform
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In Fig the authors categorize
2018-10-25
In Fig. 3, the authors categorize three types of variables that can lead to cooperation. Management (Management Variables) is a source of cooperation if managers share information with transparency. Unions, by being more responsive and integrating also lead to fostering cooperation. The unions in th
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Introduction br History br Conservation
2018-10-25
Introduction History Conservation projects and assessments Characteristics of conservation Issues Conclusion Introduction Methodology Results and analysis Conclusion Acknowledgements This study is supported by the Ministry of Science and Technology of China (Project nu
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The in vitro production and
2018-10-24
The in vitro production and expression of ECM proteins collagens I and IV and laminin differed between the perivascular derivatives. In the body, pericytes produce ECM in the subendothelial basement membrane of capillaries, while both vSMCs and pericytes produce ECM in the tunica media layer of larg
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Quiescent long term repopulating HSC LT HSC are
2018-10-24
Quiescent, long-term repopulating HSC (LT-HSC) are believed to reside predominantly in periendosteal areas of the BM characterized by low oxygen levels (Mohyeldin et al., 2010; Suda et al., 2011; Eliasson and Jönsson, 2010). Moreover, it is recently being suggested that HSC and hematopoietic progeni
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Although our results suggest that Ronin
2018-10-24
Although our results suggest that Ronin directly impacts DNA repair through the transcriptional regulation of DNA repair genes, we further sought to determine how much the canonical pluripotency factors might contribute to the transcriptional regulation of DNA repair genes. Oct4 and Sox2 are known t
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The cycling and quiescence of MaSCs has
2018-10-24
The cycling and quiescence of MaSCs has been especially difficult to study (Visvader and Stingl, 2014). It has been shown that long-lived, label-retaining cells are enriched in the MaSC/basal compartment, indicating they are slowly dividing (Shackleton et al., 2006). However, it is still unclear how
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We believe that the alteration of
2018-10-24
We believe that the alteration of cell adhesion capacity may have important functional consequences, explaining the differences that we observed in the cell cycling and quiescence of hematopoietic progenitors. Supporting this notion, here we show that the downregulation of PTPN13 or β-catenin signif
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compound library Following LPS or sepsis CMP and
2018-10-24
Following LPS or sepsis CMP and GMP pools are rapidly depleted, resulting in decreased output of GR1+MAC1+ cells, an effect largely prevented by loss of MYD88 but not of TRIF. Differences in compound library and apoptosis of myeloid progenitors in the three genotypes did not sufficiently account fo
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buy URMC-099 Given that the ECM becomes more complex as ECs
2018-10-24
Given that the ECM becomes more complex as ECs differentiate, it is of particular interest to understand the outside-in signaling that might modulate their behavior. Similar to other cell types, ECs interact with their environment in large part via the integrin family of adhesion receptors that cons
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Alzheimer s disease AD is the
2018-10-24
Alzheimer\'s disease (AD) is the most common neurodegenerative disorder. The pathological hallmarks of AD include extracellular amyloid plaques consisting mainly of Aβ42, and intracellular neurofibrillary tangles comprising mainly hyperphosphorylated tau (Serrano-Pozo et al., 2011). Previous studies
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br Results br Discussion We have developed
2018-10-24
Results Discussion We have developed an optimized and streamlined method for efficient engineering of targeted chromosomal translocations in human MSCs and iPSCs. We first generated an all-in-one plasmid system to co-express two sgRNAs, the Streptococcus pyogenes Cas9 flanked by two NLSs and
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Our current study also enabled the assessment of clonal
2018-10-24
Our current study also enabled the assessment of clonal contribution to in vivo multilineage hematopoiesis from single order SL-327 at the earliest stages of HSC precursor formation, which has allowed us to identify the earliest common precursor of B-1a and B-2 cell potential in a clonal precursor t
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Compared with D surfaces three dimensional D stem cell
2018-10-24
Compared with 2D surfaces, three-dimensional (3D) stem cell culture can facilitate substantially higher yields (Lei and Schaffer, 2013; Serra et al., 2012; Zweigerdt et al., 2011). For example, using a 3D thermoresponsive material under completely chemically defined conditions, we previously achieve
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