• Since the first studies of betaine aldehyde oxidation in

  2023-04-14

  

  Since the first studies of betaine aldehyde oxidation in rats [13], the participation of betaine in the detoxification of homocysteine has well described, considering the activity of other Calcipotriol as betaine homocysteine methyltransferase and methionine synthase. But, there is a lack of attent

• 1,4-DPCA Liaohe River situates in the southwestern part of N

  2023-04-14

  

  Liaohe River situates in the southwestern part of Northeast China and flows through Liaoning Province. Due to the rapid urbanization and industrialization, Liaohe River has become one of the most polluted rivers in China. Multitudinous organic pollutants that can induce toxicity to organisms such as

• The study by Lo http

  2023-04-14

  

  The study by Lowry et al. (2001) pointed toward functionally uncharacterized DA- and 5-HT-accumulating neurons within the DMH as a potential target for rapid nongenomic effects of CORT. Similar DA- and 5-HT-accumulating systems are distributed throughout the central and peripheral nervous systems, s

• The present work has implications for our thinking about the

  2023-04-14

  

  The present work has implications for our thinking about the effects of antidepressant (e.g. SSRIs) use on maternal care in depressed mothers which consist of approximately 10–20% of all mothers (Gjerdingen and Yawn, 2007, Susser et al., 2016), and more than 40% of depressed mothers are prescribed w

• ornidazole A highly attenuated B pertussis strain

  2023-04-14

  

  A highly attenuated B. pertussis strain, named BPZE1, has recently been described [10]. It produces enzymatically inactive pertussis toxin (PT), no dermonecrotic toxin and only trace amounts of tracheal cytotoxin. Markedly reduced lung pathology was observed in mice intranasally (i.n.) infected with

• HT modulates cortical and hippocampal pyramidal cell

  2023-04-14

  

  5-HT modulates cortical and hippocampal pyramidal cell function in a very complex manner, since most 5-HT receptor subtypes (excitatory as well as inhibitory) are expressed on pyramidal Furegrelate sodium salt as well as GABAergic interneurons that exert inhibitory control over pyramidal cells (Leis

• br Materials and methods br Results To explore the potential

  2023-04-14

  

  Materials and methods Results To explore the potential role of autophagy in drug resistance, we firstly performed immunohistochemistry to compare the Mouse iPSC Chemical Reprogramming Cocktails Kit australia of p62 in paired primary, metastatic, and recurrent tumor tissues from 26 ovarian can

• The phylogenetic relationship demonstrates that both bovine

  2023-04-14

  

  The phylogenetic relationship demonstrates that both bovine and porcine 12/15-LO is more related to the human enzyme than the rabbit enzyme, despite the fact that the rabbit reticulocyte enzyme is a 15-lipoxygenase. The rabbit is one single species that expresses a 12/15 LO with 15-LO activity while

• Based on the extracellular domain structures we can

  2023-04-14

  

  Based on the extracellular domain structures, we can infer that the dimer arrangement of GABAB receptor will undergo substantial changes upon receptor activation (Geng et al., 2013). First, agonist-stimulated closure of GABAB1 VFT would cause an upward rotation of its LB2 domain, coupled with an inw

• br ASK in multiple sclerosis and optic

  2023-04-14

  

  ASK1 in multiple sclerosis and optic neuritis Multiple sclerosis (MS), a chronic inflammatory demyelinating disease of the central nervous system (CNS), is the most common neurological disease among young adults in the United States and Europe (Dutta and Trapp, 2011). Although MS primarily affect

• br Results br Discussion AP a heterodimeric

  2023-04-14

  

  Results Discussion AP-1, a heterodimeric transcription factor comprising various combinations of FOS, JUN, MAF, ATF, and CREB family proteins, has been known to play a pivotal role in leukocyte development for decades (Liebermann et al., 1998; Valledor et al., 1998). However, its participatio

• The radiographic correlate will be similarly

  2023-04-14

  

  The radiographic correlate will be similarly important for the success of other non-VEGF TKIs, such as those targeting the epidermal growth factor receptor expressed in 50% of high-grade primary Nitrotetrazolium Blue chloride neoplasms. It has been reported that icotinib and gefitinib, epidermal gro

• Therefore in the present study we first examined

  2023-04-13

  

  Therefore, in the present study, we first examined the ATRAP Ketoconazole in human leukocytes of healthy subjects. We next analyzed possible relevant clinical factors affecting ATRAP expression in leukocytes of patients with NCDs. Furthermore, we examined the possible effect of ATRAP downregulation

• Moxidectin br AR expression in breast tissue

  2023-04-13

  

  AR expression in breast tissue Although androgenic signalling is chiefly associated with the development and maintenance of primary and secondary male characteristics, especially during puberty when the testes are by far the major source of testosterone, the AR also plays important functions in f

• Sixth significant progress has been made during

  2023-04-13

  

  Sixth, significant progress has been made during the last few years regarding the molecular mechanisms underlying the activation of AMPK and this should aid to develop more potent and specific compounds. Information from crystallographic structures combined with computer-based drug design hold promi

15877 records 302/1059 page Previous Next First page 上5页 301302303304305 下5页 Last page