• Funding US Centers for Disease Control

  2019-06-28

  

  Funding US Centers for Disease Control and Prevention, US President\'s Malaria Initiative, Doris Duke Charitable Foundation, and Alpha Omega Alpha Honor Society. Declaration of interests Abstract Background Injuries are the cause of almost 6 million deaths every year, with 15–20% of these assoc

• This is the first report describing the occurrence

  2019-06-28

  

  This is the first report describing the occurrence of HLH in a patient with refractory CLL who had started Ibrutinib treatment. Hemophagocytic lymphohistiocytosis (HLH) is a rare and frequently fatal disorder characterized by an ineffective T-cell and NK response resulting in an exuberant cytokine p

• br Discussion We evaluated and determined the incidence

  2019-06-28

  

  Discussion We evaluated and determined the incidence and severity of subjective reports of dyspepsia symptoms due to dabigatran. Based on the results of the RE-LY trial [4], the AE that was significantly more common with dabigatran than with warfarin was dyspepsia. In the sub-group (326 Japanese

• br Statistical power and analysis A description of

  2019-06-28

  

  Statistical power and analysis A description of the statistical analysis of the study has been published previously [23]. For the analysis of the results at the 5-year time point, comparisons were expressed graphically using 95% confidence intervals. Statistical analysis was performed using SPSS

• br ECM cancer and metastasis

  2019-06-28

  

  ECM, cancer and metastasis For bromodomain to become cancerous they must acquire the ability to survive, grow and invade leading to malignant transformation, tumour formation and ultimately overt secondary metastasis. Abnormal ECM can promote these abilities and is a well-documented hallmark of c

• At autopsy approximately cm of blood and

  2019-06-28

  

  At autopsy, approximately 180cm3 of blood and clots were found inside the pericardial cavity. Careful inspection of the Adenosine showed a deep lesion, 2mm in length, on the antero-lateral aspect of the vessel (Fig. 1) 2cm above the valvular plane (Fig. 2). On the medial aspect of the right atrium,

• Pilsicainide might increase hERG proteins

  2019-06-28

  

  Pilsicainide might increase hERG proteins via facilitating the transcription of hERG from DNA to RNA or the translation of hERG RNA into hERG protein. Qualitative RT-PCR demonstrated the absence of an increase in hERG mRNA expression levels after pilsicainide treatment (Supplemental Fig. S2), indica

• In Telek Ayove and colleagues

  2019-06-28

  

  In , Telek Ayove and colleagues report a comparison of the Dual Path Platform (DPP) Syphilis Screen and Confirm test (Chembio Diagnostic Systems, Medford, NY, USA) with non-treponemal (RPR) and treponemal (TPHA) serological tests for diagnosis of yaws in two remote communities in Papua New Guinea wi

• A922500 structure br Clinical evidence to support that PES p

  2019-06-27

  

  Clinical evidence to support that PES predicts cardiac events in BS Brugada et al. were the first to propose that inducibility of sustained ventricular arrhythmias with PES is useful to identify patients who are at high risk of SCD [3]. During follow-up of patients with spontaneous type 1 Brugada

• Introduction Neuroblastoma NB which arises

  2019-06-27

  

  Introduction Neuroblastoma (NB), which arises from embryonal neural crest cells, is the most common extra-cranial solid tumor of childhood and accounts for more than 15% of all child cancer death [1,2]. Patients with NB frequently manifest disseminated disease at first visit and prognosis of these

• La representaci n colectiva de

  2019-06-27

  

  La representación colectiva de los indígenas se caracteriza por el tono apologético, idealizado, en el que el uso abundante de los superlativos contribuye HOSu resaltar hiperbólicamente la naturaleza pacífica del nativo como “buen salvaje”: Siguiendo el esquema de las oposiciones binarias, Las Casa

• O ensaio de Volodia Teitelboim enfatizou os discursos de Fid

  2019-06-27

  

  O ensaio de Volodia Teitelboim enfatizou os discursos de Fidel Castro desde quando seu grupo assumiu o poder em Cuba, logo após Fmoc-Gly-OH vitória em Sierra Maestra. Sua habilidade com as palavras foi destacada por Teitelboim, bem como seu caráter de coragem e retidão. Tais qualidades do líder revo

• We have recently completed a prospective randomized feasibil

  2019-06-27

  

  We have recently completed a prospective randomized feasibility study of de-escalated bisphosphonate treatment with intravenous pamidronate in patients with metastatic breast cancer to bone [7]. Here we report on an analysis utilizing data from this trial aimed at comparing BPI and FACT-BP and to co

• Macrophages in bone metastasis main

  2019-06-27

  

  Macrophages in bone metastasis – main outstanding questions: Conflict of interest statement Acknowledgements IV was supported by a generous grant from Weston Park Hospital Cancer Charity, Sheffield, UK. Introduction In recent years there has been increasing interest in the role of bone-ta

• br Materials and methods br Results br Discussion Osteosarco

  2019-06-27

  

  Materials and methods Results Discussion Osteosarcoma derives from primitive bone-forming mesenchymal cells and is the most common type of primary bone malignancy [20]. Over the past few decades, the introduction of combinatorial chemotherapy has improved the 5-year overall survival rate of

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